Carcinoma is still the leading cause of death globally, regardless of progress in their treatments and detection. Conventional chemotherapeutic agents used in the treatment of tumors have non-specific toxicity. Apart from tumor, they are attacking healthy cells as well, which leads to various side effects. Furthermore, tumor cells may eventually develop resistance to chemotherapy. Therefore, the need for new antitumor approaches is increasing every day. One of the promising approaches is photodynamic therapy. This therapy combines separately three nontoxic components: oxygen, photosensitizer and light. After the photosensitizer is irradiated with the light of the appropriate wavelength in the presence of the molecular oxygen, a highly reactive and toxic singlet oxygen is created. The latter can cause oxidative damage to the tissue in which it is present. Therefore, it is very important that the photosensitizer is localized solely in the tumor tissue so as to avoid damaging the healthy tissue. In this respect, so far the most effective compounds were porphyrins. Solubility, distribution within tumor and the ability to pass through the tumor membrane greatly influence the specificity of a porphyrin. There were different efforts to increase mentioned specificity, but the most efficient way was shown to be conjugation of porphyrin with certain biomolecules. Peptides are easily accessible and can be simply modified, and because of that they are proved to be excellent conjugation vectors. In this work, the conjugation of porphyrin with antimicrobial peptide nisin is shown. Amphiphilic properties of the conjugate and the presence of nisin in its structure are expected to enhance solubility of the photosensitizer and its penetration through the tumor membrane. This can positively affect the specificity and efficiency of the photosensitizer, thus photodynamic therapy itself.