prikaz prve stranice dokumenta Glia in amyotrophic lateral sclerosis and spinal cord injury: common therapeutic targets
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Glia in amyotrophic lateral sclerosis and spinal cord injury: common therapeutic targets
Croatian medical journal, 60 (2019), 2; 109-120. https://doi.org/10.3325/cmj.2019.60.109
Ban, Jelena; Mladinic, Miranda; Sámano, Cynthia; Munitic, Ivana

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Ban, J., Mladinic, M., Sámano, C. i Munitic, I. (2019). Glia in amyotrophic lateral sclerosis and spinal cord injury: common therapeutic targets. Croatian medical journal, 60. (2), 109-120. doi: 10.3325/cmj.2019.60.109

Ban, Jelena, et al. "Glia in amyotrophic lateral sclerosis and spinal cord injury: common therapeutic targets." Croatian medical journal, vol. 60, br. 2, 2019, str. 109-120. https://doi.org/10.3325/cmj.2019.60.109

Ban, Jelena, Miranda Mladinic, Cynthia Sámano i Ivana Munitic. "Glia in amyotrophic lateral sclerosis and spinal cord injury: common therapeutic targets." Croatian medical journal 60, br. 2 (2019): 109-120. https://doi.org/10.3325/cmj.2019.60.109

Ban, J., et al. (2019) 'Glia in amyotrophic lateral sclerosis and spinal cord injury: common therapeutic targets', Croatian medical journal, 60(2), str. 109-120. doi: 10.3325/cmj.2019.60.109

Ban J, Mladinic M, Sámano C, Munitic I. Glia in amyotrophic lateral sclerosis and spinal cord injury: common therapeutic targets. Croatian medical journal [Internet]. 30.04.2019. [pristupljeno 28.10.2024.];60(2):109-120. doi: 10.3325/cmj.2019.60.109

J. Ban, M. Mladinic, C. Sámano i I. Munitic, "Glia in amyotrophic lateral sclerosis and spinal cord injury: common therapeutic targets", Croatian medical journal, vol. 60, br. 2, str. 109-120, Travanj 2019. [Online]. Dostupno na: https://urn.nsk.hr/urn:nbn:hr:193:669405. [Citirano: 28.10.2024.]

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Podaci o radu
Naslov (engleski)Glia in amyotrophic lateral sclerosis and spinal cord injury: common therapeutic targets
AutorJelena Ban
AutorMiranda Mladinic
AutorCynthia Sámano
AutorIvana Munitic
Autorova ustanovaSveučilište u Rijeci
(Fakultet biotehnologije i razvoja lijekova)
Znanstveno / umjetničko
područje, polje i grana		INTERDISCIPLINARNA PODRUČJA ZNANOSTI
Biotehnologija u biomedicini (prirodno područje, biomedicina i zdravstvo, biotehničko područje)
Sažetak (engleski)
The toolkit for repairing damaged neurons in amyotrophic lateral sclerosis (ALS) and spinal cord injury (SCI) is extremely limited. Here, we reviewed the in vitro and in vivo studies and clinical trials on nonneuronal cells in the neurodegenerative processes common to both these conditions. Special focus was directed to microglia and astrocytes, because their activation and proliferation, also known as neuroinflammation, is a key driver of neurodegeneration. Neuroinflammation is a multifaceted process that evolves during the disease course, and can be either beneficial or toxic to neurons. Given the fundamental regulatory functions of glia, pathogenic mechanisms in neuroinflammation represent promising therapeutic targets. We also discussed neuroprotective, immunosuppressive, and stem-cell based approaches applicable to both ALS and SCI.
Ključne riječi (engleski)
Jezikengleski
Vrsta publikacijeZnanstveni rad - Pregledni rad
Status objaveObjavljen
Vrsta recenzijeRecenziran - međunarodna recenzija
Verzija publikacijeObjavljena verzija rada (izdavačev PDF)
Naslov časopisaCroatian medical journal
Brojčani podacivol. 60, br. 2, str. 109-120
p-ISSN0353-9504
e-ISSN1332-8166
DOIhttps://doi.org/10.3325/cmj.2019.60.109
URN:NBNurn:nbn:hr:193:669405
Datum objave publikacije2019-04-30
URL dokumentahttp://www.cmj.hr/2019/60/2/31044582.htm
Vrsta resursaTekst
Prava pristupaOtvoreni pristup
Uvjeti korištenjaIkona licence Imenovanje-Nekomercijalno-Bez prerada 4.0 međunarodna (CC BY-NC-ND 4.0)
Datum i vrijeme pohrane2019-09-09 14:20:48