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The IVF Outcome Counseling Based on the Model Combining DHEAS and Age in Patients with Low AMH Prior to the First Cycle of GnRH Antagonist Protocol of Ovarian Stimulation
International Journal of Endocrinology, 2013 (2013); 637919. https://doi.org/10.1155/2013/637919
Alebić, Miro Šimun; Stojanović, Nataša; Žuvić-Butorac, Marta

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Alebić, M. Š., Stojanović, N. i Žuvić Butorac, M. (2013). The IVF Outcome Counseling Based on the Model Combining DHEAS and Age in Patients with Low AMH Prior to the First Cycle of GnRH Antagonist Protocol of Ovarian Stimulation. International Journal of Endocrinology, 2013.. doi: 10.1155/2013/637919

Alebić, Miro Šimun, et al. "The IVF Outcome Counseling Based on the Model Combining DHEAS and Age in Patients with Low AMH Prior to the First Cycle of GnRH Antagonist Protocol of Ovarian Stimulation." International Journal of Endocrinology, vol. 2013, 2013. https://doi.org/10.1155/2013/637919

Alebić, Miro Šimun, Nataša Stojanović i Marta Žuvić Butorac. "The IVF Outcome Counseling Based on the Model Combining DHEAS and Age in Patients with Low AMH Prior to the First Cycle of GnRH Antagonist Protocol of Ovarian Stimulation." International Journal of Endocrinology 2013 (2013). https://doi.org/10.1155/2013/637919

Alebić, M. Š., Stojanović, N. i Žuvić Butorac, M. (2013) 'The IVF Outcome Counseling Based on the Model Combining DHEAS and Age in Patients with Low AMH Prior to the First Cycle of GnRH Antagonist Protocol of Ovarian Stimulation', International Journal of Endocrinology, 2013. doi: 10.1155/2013/637919

Alebić MŠ, Stojanović N, Žuvić Butorac M. The IVF Outcome Counseling Based on the Model Combining DHEAS and Age in Patients with Low AMH Prior to the First Cycle of GnRH Antagonist Protocol of Ovarian Stimulation. International Journal of Endocrinology [Internet]. 2013. [pristupljeno 27.10.2024.];2013. doi: 10.1155/2013/637919

M. Š. Alebić, N. Stojanović i M. Žuvić Butorac, "The IVF Outcome Counseling Based on the Model Combining DHEAS and Age in Patients with Low AMH Prior to the First Cycle of GnRH Antagonist Protocol of Ovarian Stimulation", International Journal of Endocrinology, vol. 2013, 2013. [Online]. Dostupno na: https://urn.nsk.hr/urn:nbn:hr:193:368611. [Citirano: 27.10.2024.]

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Naslov (engleski)The IVF Outcome Counseling Based on the Model Combining DHEAS and Age in Patients with Low AMH Prior to the First Cycle of GnRH Antagonist Protocol of Ovarian Stimulation
AutorMiro Šimun Alebić https://orcid.org/0000-0002-3358-5055
AutorNataša Stojanović https://orcid.org/0000-0001-8053-4771
AutorMarta Žuvić-Butorac https://orcid.org/0000-0001-9709-1508
MBZ: 173412
Autorova ustanovaSveučilište u Rijeci
(Fakultet biotehnologije i razvoja lijekova)
Znanstveno / umjetničko
područje, polje i grana		BIOMEDICINA I ZDRAVSTVO
Kliničke medicinske znanosti
Ginekologija i opstetricija
Sažetak (engleski)
Objective. To investigate the endocrine and/or clinical characteristics of women with low anti-Müllerian hormone (AMH) that could improve the accuracy of IVF outcome prediction based on the female age alone prior to the first GnRH antagonist IVF cycle. Methods. Medical records of 129 patients with low AMH level (<6.5 pmol/L) who underwent their first GnRH antagonist ovarian stimulation protocol for IVF/ICSI were retrospectively analyzed. The main outcome measure was the area under the ROC curve (AUC-ROC) for the models combining age and other potential predictive factors for the clinical pregnancy. Results. Clinical pregnancy rate (CPR) per initiated cycles was 11.6%. For the prediction of clinical pregnancy, DHEAS and age showed AUC-ROC of 0.726 (95%CI 0.641–0.801) and 0.662 (95%CI 0.573–0.743), respectively. The predictive accuracy of the model combining age and DHEAS (AUC-ROC 0.796; 95%CI 0.716–0.862) was significantly higher compared to that of age alone (). In patients <37.5 years with DHEAS  pmol/L, 60% (9/15) of all pregnancies were achieved with CPR of 37.5%. Conclusions. DHEAS appears to be predictive for clinical pregnancy in younger women (<37.5 years) with low AMH after the first GnRH antagonist IVF cycle. Therefore, DHEAS-age model could refine the pretreatment counseling on pregnancy prospects following IVF.
Ključne riječi (engleski)
Jezikengleski
Vrsta publikacijeZnanstveni rad - Izvorni znanstveni rad
Status objaveObjavljen
Vrsta recenzijeRecenziran - međunarodna recenzija
Verzija publikacijeObjavljena verzija rada (izdavačev PDF)
Naslov časopisaInternational Journal of Endocrinology
Brojčani podacivol. 2013, 637919
BPC800 USD
p-ISSN2224-0721
e-ISSN2307-1427
DOIhttps://doi.org/10.1155/2013/637919
URN:NBNurn:nbn:hr:193:368611
Datum objave publikacije2013
URL dokumentahttps://www.hindawi.com/journals/ije/apc/
Vrsta resursaTekst
Prava pristupaOtvoreni pristup
Uvjeti korištenjaIkona licence Zaštićeno autorskim pravom.
Datum i vrijeme pohrane2018-09-30 12:18:49