prikaz prve stranice dokumenta The interaction of schizophrenia-related proteins DISC1 and NDEL1, in light of the newly identified domain structure of DISC1
  Preuzmi
PDF 876.47 KB
Znanstveni rad - Pregledni rad
The interaction of schizophrenia-related proteins DISC1 and NDEL1, in light of the newly identified domain structure of DISC1
Communicative and Integrative Biology, 10 (2017), 4; 4. https://doi.org/10.1080/19420889.2017.1335375
Bradshaw, Nicholas J.

Citirajte ovaj rad

Bradshaw, N. J. (2017). The interaction of schizophrenia-related proteins DISC1 and NDEL1, in light of the newly identified domain structure of DISC1. Communicative and Integrative Biology, 10. (4), e1335375. doi: 10.1080/19420889.2017.1335375

Bradshaw, Nicholas J.. "The interaction of schizophrenia-related proteins DISC1 and NDEL1, in light of the newly identified domain structure of DISC1." Communicative and Integrative Biology, vol. 10, br. 4, 2017, str. e1335375. https://doi.org/10.1080/19420889.2017.1335375

Bradshaw, Nicholas J.. "The interaction of schizophrenia-related proteins DISC1 and NDEL1, in light of the newly identified domain structure of DISC1." Communicative and Integrative Biology 10, br. 4 (2017): e1335375. https://doi.org/10.1080/19420889.2017.1335375

Bradshaw, N. J. (2017) 'The interaction of schizophrenia-related proteins DISC1 and NDEL1, in light of the newly identified domain structure of DISC1', Communicative and Integrative Biology, 10(4), str. e1335375. doi: 10.1080/19420889.2017.1335375

Bradshaw NJ. The interaction of schizophrenia-related proteins DISC1 and NDEL1, in light of the newly identified domain structure of DISC1. Communicative and Integrative Biology [Internet]. 02.06.2017. [pristupljeno 19.04.2024.];10(4):e1335375. doi: 10.1080/19420889.2017.1335375

N. J. Bradshaw, "The interaction of schizophrenia-related proteins DISC1 and NDEL1, in light of the newly identified domain structure of DISC1", Communicative and Integrative Biology, vol. 10, br. 4, str. e1335375, Lipanj 2017. [Online]. Dostupno na: https://urn.nsk.hr/urn:nbn:hr:193:950901. [Citirano: 19.04.2024.]

Za citiranje koristite ovu mrežnu adresu: https://urn.nsk.hr/urn:nbn:hr:193:950901
Prijavite se u repozitorij kako biste mogli spremiti objekt u svoju listu.
Podaci o radu
Naslov (engleski)The interaction of schizophrenia-related proteins DISC1 and NDEL1, in light of the newly identified domain structure of DISC1
AutorNicholas J. Bradshaw
Autorova ustanovaSveučilište u Rijeci
(Fakultet biotehnologije i razvoja lijekova)
Znanstveno / umjetničko
područje, polje i grana		BIOTEHNIČKE ZNANOSTI
Biotehnologija
Biologija
Sažetak (engleski)
DISC1 and NDEL1 are both key proteins in cortical neurodevelopment, which are each also implicated in the pathogenesis of mental illness. That the two proteins interact with each other in a functionally important manner is well established, but two distinct binding domains for NDEL1 on DISC1 have been proposed. A partial domain structure for DISC1 has recently been described, consisting of 4 structured regions referred to as “D,” “I,” “S” and “C” respectively, with one of the NDEL1 binding sites lying in the “C” region of DISC1. In light of this domain structure, it can be deduced that this site is the likely location at which NDEL1 binds, although the other proposed site (which lies in the DISC1 “I” and “S” regions) may indirectly impact on DISC1-NDEL1 interactions through determination of the oligomeric state of DISC1.
Ključne riječi (engleski)
Jezikengleski
Vrsta publikacijeZnanstveni rad - Pregledni rad
Status objaveObjavljen
Vrsta recenzijeRecenziran - međunarodna recenzija
Verzija publikacijeObjavljena verzija rada (izdavačev PDF)
Naslov časopisaCommunicative and Integrative Biology
Brojčani podacivol. 10, br. 4, str. e1335375, 4
BPC0 CHF
p-ISSN1942-0889
DOIhttps://doi.org/10.1080/19420889.2017.1335375
URN:NBNurn:nbn:hr:193:950901
Datum objave publikacije2017-06-02
URL dokumentahttps://www.tandfonline.com/doi/full/10.1080/19420889.2017.1335375
Vrsta resursaTekst
Prava pristupaOtvoreni pristup
Uvjeti korištenjaIkona licence Imenovanje-Nekomercijalno-Bez prerada 4.0 međunarodna (CC BY-NC-ND 4.0)
Datum i vrijeme pohrane2018-09-14 11:14:48