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undergraduate thesis
mRNA cjepiva protiv bolesti COVID-19
2022. urn:nbn:hr:193:017138
Montan, Andrea
University of Rijeka
Faculty of Biotechnology and Drug Development

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Montan, A. (2022). mRNA cjepiva protiv bolesti COVID-19 (Undergraduate thesis). Rijeka: University of Rijeka. Retrieved from https://urn.nsk.hr/urn:nbn:hr:193:017138

Montan, Andrea. "mRNA cjepiva protiv bolesti COVID-19." Undergraduate thesis, University of Rijeka, 2022. https://urn.nsk.hr/urn:nbn:hr:193:017138

Montan, Andrea. "mRNA cjepiva protiv bolesti COVID-19." Undergraduate thesis, University of Rijeka, 2022. https://urn.nsk.hr/urn:nbn:hr:193:017138

Montan, A. (2022). 'mRNA cjepiva protiv bolesti COVID-19', Undergraduate thesis, University of Rijeka, accessed 19 April 2024, https://urn.nsk.hr/urn:nbn:hr:193:017138

Montan A. mRNA cjepiva protiv bolesti COVID-19 [Undergraduate thesis]. Rijeka: University of Rijeka; 2022 [cited 2024 April 19] Available at: https://urn.nsk.hr/urn:nbn:hr:193:017138

A. Montan, "mRNA cjepiva protiv bolesti COVID-19", Undergraduate thesis, University of Rijeka, Rijeka, 2022. Available at: https://urn.nsk.hr/urn:nbn:hr:193:017138

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Metadata
TitlemRNA cjepiva protiv bolesti COVID-19
Title (english)mRNA vaccines against COVID-19
AuthorAndrea Montan
MentorIvana Munitić (mentor)
Committee memberIgor Jurak (predsjednik povjerenstva)
Committee memberIlija Brizić (član povjerenstva)
Committee memberIvana Munitić (član povjerenstva)
GranterUniversity of Rijeka
(Faculty of Biotechnology and Drug Development)
Rijeka
Defense date and country2022, Croatia
Scientific / art field,
discipline and subdiscipline		BIOTECHNICAL SCIENCES
Biotechnology
Abstract
Teški akutni respiratorni sindrom koronavirus 2, virus je koji se pojavio krajem 2019. godine u Wuhanu, proširio svijetom i uzrokovao pandemiju koronavirusne bolesti 19. Zbog brzog širenja virusa i često eksponencijalnog rasta zaraženih, javili su se brojni problemi u zdravstvu, ali i svjetskoj ekonomiji i gospodarstvu. Kako bi se spriječilo širenje virusa i smanjio broj pacijenata većina država uvodila je stroge epidemiološke mjere te je zatvarala svoje granice. Pandemija COVID-19 zahtijevala je brzu reakciju znanstvenika te su nekoliko dana nakon sekvenciranja genoma virusa započela brojna istraživanja usmjerena razumijevanju biologije virusa te terapijskim i preventivnim pristupima protiv COVID-19 bolesti. Pritom su uspješno iskorištena prethodna znanja o cjepivima i modernoj mRNA tehnologiji te je upravo mRNA cjepivo bilo prvo odobreno cjepivo protiv koronavirusne bolesti. mRNA tehnologija u posljednjih deset godina doživjela je velik razvoj te je danas često korištena tehnika u eksperimentalnim pristupima liječenju raka. mRNA molekule za cjepiva se sintetiziraju in vitro na temelju sekvence genoma ciljanog patogena te se cijepljenjem unose u organizam nakon čega aktiviraju urođeni i stečeni imunosni odgovor. Stoga se mRNA tehnologija ubraja u važne pristupe prevencije COVID-19 bolesti te se očekuje da će pridonijeti završetku pandemije COVID-19.
Abstract (english)
Severe acute respiratory syndrome coronavirus 2, appeared in late 2019. in Wuhan, spread around the world and caused coronavirus pandemic. Due to rapid spread of the virus and almost an exponential growth of those infected individuals, numerous problems arose in healthcare, as well as in the world economy. In order to prevent spread of the virus and reduce the number of patients, most states introduced strict epidemiological measures. The COVID-19 pandemic required a quick response from scientists, so few days after sequencing of the virus genome, intense research began to understand the biology of the virus, and preventive and therapeutic measures against COVID-19 infection. Previous knowledge of vaccines and modern mRNA technology has been used and mRNA vaccine became first approved vaccine against coronavirus disease. mRNA technology had a major development in the last ten years and today it is often used technique in experimental tumor targetting. mRNA molecules are synthesized in vitro based on the pathogen genome sequence and are introduced into the body by vaccination. After vaccination they stimulate a protective immune response. mRNA technology is one of the major upcoming therapeutic approaches and will likely contribute to ending COVID-19 pandemic.
Keywords
Keywords (english)
Languagecroatian
URN:NBNurn:nbn:hr:193:017138
Study programmeTitle: Biotechnology and drug research
Study programme type: university
Study level: undergraduate
Academic / professional title: sveučilišni/a prvostupnik/prvostupnica biotehnologije i istraživanja lijekova (sveučilišni/a prvostupnik/prvostupnica biotehnologije i istraživanja lijekova)
Type of resourceText
File originBorn digital
Access conditionsOpen access
Terms of useLicence In copyright icon
Created on2022-10-24 12:44:50