The familial inheritance mechanism of different phenotypes caused by parental drug use consists of genetic and environmental factors. Epigenetic factors can govern the activation and silencing of gene expression and have been associated with long-term neuroplastic changes related to drug use in humans and animal models. Such changes may persist over several generations even though exposure to the original stimulus has been discontinued. Therefore, epigenetic transgenerational inheritance suggests a mechanism for the influence of parental drug use on several generations of offspring. This research aimed to examine how volatilized methamphetamine (vMETH) affects the developmental cycle of Drosophila melanogaster. Using the FlyBong method, we administered vMETH to a large group of males, from which we then selected 10% that showed the highest locomotor response and mated them with virgins that were not exposed to vMETH. The impact of exposure of F0 fathers on the development speed and the number of F1 and F2 generation offspring was monitored. In the F1 generation, the results showed a trend of an increased number of pupae and both male and female offspring in the group exposed to vMETH. While in the F2 generation, there is a visible trend of an increased number of pupae and female offspring, this trend is not present in male offspring. Therefore, the results suggest a possible influence of vMETH on the developmental cycle of Drosophila melanogaster, and such an effect has potential transgenerational characteristics. In order to confirm these hypotheses, these preliminary results need to be validated by more detailed studies of the influence of vMETH on the development cycle. It is necessary to determine this effect's specific mechanisms and hereditary properties.