prikaz prve stranice dokumenta Antimicrobial and prebiotic activity of Pilosella hoppeana
  Download
PDF 1.65 MB
master's thesis
Antimicrobial and prebiotic activity of Pilosella hoppeana
2024. urn:nbn:hr:193:745074
Glad, Dorian
University of Rijeka
Faculty of Biotechnology and Drug Development

Cite this document

Glad, D. (2024). Antimicrobial and prebiotic activity of Pilosella hoppeana (Master's thesis). Rijeka: University of Rijeka. Retrieved from https://urn.nsk.hr/urn:nbn:hr:193:745074

Glad, Dorian. "Antimicrobial and prebiotic activity of Pilosella hoppeana." Master's thesis, University of Rijeka, 2024. https://urn.nsk.hr/urn:nbn:hr:193:745074

Glad, Dorian. "Antimicrobial and prebiotic activity of Pilosella hoppeana." Master's thesis, University of Rijeka, 2024. https://urn.nsk.hr/urn:nbn:hr:193:745074

Glad, D. (2024). 'Antimicrobial and prebiotic activity of Pilosella hoppeana', Master's thesis, University of Rijeka, accessed 23 January 2025, https://urn.nsk.hr/urn:nbn:hr:193:745074

Glad D. Antimicrobial and prebiotic activity of Pilosella hoppeana [Master's thesis]. Rijeka: University of Rijeka; 2024 [cited 2025 January 23] Available at: https://urn.nsk.hr/urn:nbn:hr:193:745074

D. Glad, "Antimicrobial and prebiotic activity of Pilosella hoppeana", Master's thesis, University of Rijeka, Rijeka, 2024. Available at: https://urn.nsk.hr/urn:nbn:hr:193:745074

Please login to the repository to save this object to your list.
Metadata
TitleAntimicrobial and prebiotic activity of Pilosella hoppeana
Title (croatian)Antimikrobna i prebiotska aktivnost Pilosella hoppeane
AuthorDorian Glad
MentorStribor Marković (mentor)
Committee memberIgor Jurak (predsjednik povjerenstva)
GranterUniversity of Rijeka
(Faculty of Biotechnology and Drug Development)
Rijeka
Defense date and country2024-09-24, Croatia
Scientific / art field,
discipline and subdiscipline		BIOTECHNICAL SCIENCES
Biotechnology
Abstract
Antimicrobial resistance (AMR) poses a critical global health challenge, with Staphylococcus aureus, Pseudomonas aeruginosa, and Enterococcus faecalis among the top pathogens causing AMR-related deaths. This study explores the antimicrobial and prebiotic potential of Pilosella officinarum and three Pilosella hoppeana extracts (collected in June, July, and August 2023) against these pathogens and their prebiotic impact on Lactobacillus casei. Using broth microdilution assays, we evaluated the antimicrobial activity of water and ethanol extracts and their prebiotic effects compared to inulin, GOS, and FOS. Ethanol extracts showed greater antibacterial activity than water extracts. Notably, Pilosella officinarum ethanol extracts were effective against S. aureus, E. faecalis, and P. aeruginosa, while Pilosella hoppeana August extracts targeted only P. aeruginosa. None of the extracts demonstrated prebiotic activity on L. casei. These findings suggest Pilosella species as promising antimicrobial agents, particularly against P. aeruginosa.
Abstract (croatian)
Antimikrobna rezistencija (AMR) predstavlja ozbiljan globalni zdravstveni izazov, pri čemu su Staphylococcus aureus, Pseudomonas aeruginosa i Enterococcus faecalis među vodećim patogenima koji uzrokuju smrti povezane s AMR-om. Ovo istraživanje ispituje antimikrobni i prebiotički potencijal Pilosella officinarum i tri ekstrakta Pilosella hoppeana (prikupljenih u lipnju, srpnju i kolovozu 2023.) protiv ovih patogena te njihov prebiotički učinak na Lactobacillus casei. Koristeći test mikrorazrjeđivanja bujona, procijenili smo antimikrobnu aktivnost vodenih i etanolnih ekstrakata te njihov prebiotički učinak u usporedbi s inulinom, GOS-om i FOS-om. Etanolni ekstrakti pokazali su veću antibakterijsku aktivnost od vodenih. Ekstrakti Pilosella officinarum u etanolu bili su učinkoviti protiv S. aureus, E. faecalis i P. aeruginosa, dok su ekstrakti Pilosella hoppeana prikupljeni u kolovozu bili učinkoviti samo protiv P. aeruginosa. Nijedan ekstrakt nije pokazao prebiotičku aktivnost na L. casei. Ovi rezultati ukazuju na potencijal vrsta Pilosella kao izvora učinkovitih antimikrobnih sredstava, osobito protiv P. aeruginosa.
Keywords
Keywords (croatian)
Languageenglish
URN:NBNurn:nbn:hr:193:745074
Study programmeTitle: Biotechnology in medicine
Study programme type: university
Study level: graduate
Academic / professional title: magistar/magistra biotehnologije u medicini (magistar/magistra biotehnologije u medicini)
Type of resourceText
File originBorn digital
Access conditionsOpen access
Terms of useLicence In copyright icon
Created on2024-09-22 09:18:16