Human-computer interaction (HCI) plays a crucial role in the development of innovative technological solutions that significantly improve the quality of life for people with neurodegenerative diseases, such as Alzheimer's disease, Parkinson's disease, and amyotrophic lateral sclerosis (ALS). HCI systems, which include advanced interfaces tailored to the needs of patients, can help preserve cognitive functions, facilitate communication, and increase the autonomy and independence of affected individuals. In medicine, HCI technologies are used in various forms, from simple software solutions to sophisticated medical devices. For example, deep brain stimulation (DBS) and Neuralink represent advanced methods that enable direct interaction with the brain, significantly improving therapeutic outcomes in neurodegenerative diseases. Additionally, virtual reality (VR) offers new possibilities for cognitive rehabilitation and therapy, allowing simulations and exercises tailored to the needs of patients. The integration of these technologies into everyday medical practice not only improves the quality of care but also reduces the burden on the healthcare system. Continuous patient monitoring, personalized therapy, and enhanced adaptability to individual needs enable more effective and targeted treatment. These advances indicate a significant transformation in the approach to treating neurodegenerative diseases, with the potential for further development in the future.